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Заметки детского врача

40854 @DrButriy

Канал педиатра Бутрия Сергея

Заметки детского врача

7 лет назад
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2) Британцы также суперпозитивны в этом вопросе:
2. The safety of rubella-containing vaccines in pregnancy
In the USA, UK and Germany, hundreds of women have been followed through active surveillance since the 1970s. This includes 293 who were vaccinated with rubella-containing vaccine within 6 weeks of their last menstrual period. None of the babies had permanent abnormalities compatible with congenital rubella syndrome (CRS) [1]. A small number of babies (around 16) had evidence that they had been exposed to the weakened vaccine virus (from blood tests) but there was no sign that the vaccine had affected the development of the infant.
Very large measles-rubella vaccination campaigns, run between 2001 and 2008, have targeted women of child-bearing age in South America and Iran [2] [3] [4] [5] [6]. Comprehensive, prospective surveillance of pregnant women during these campaigns has provided further substantial evidence of the safety of measles and rubella containing vaccines in pregnancy. During these campaigns over 30,000 pregnant women inadvertently received MR vaccine. The vaccine had been given either during pregnancy (the majority were less than 12 weeks pregnant) or up to 30 days before these women had conceived.
In the above studies about 3000 women were susceptible to rubella, meaning they were not already immune and so at potential risk of the virus passing to the baby. Extensive follow-up of the outcome of these pregnancies was very reassuring. Whilst a very small number of babies were shown to have been exposed to the weakened vaccine virus in the womb, no babies developed Congenital rubella syndrome (CRS). There was also no increase in the risk of miscarriage or stillbirth in pregnant women who were susceptible (non-immune) when they were vaccinated when compared to those protected by prior immunity [7].
These large-scale vaccination programmes were carried out at a time when natural rubella infection was high in those countries and so it is was very unlikely that an infant with the clinical features of CRS would be missed [2]. During 2001 to 2002, 56 infants with CRS were reported to the San Paulo State Health Department. None of these were born to mothers vaccinated in pregnancy and so it was concluded that all were due to natural infection [7]].

https://www.gov.uk/government/publications/vaccine-in-pregnancy-advice-for-pregnant-women/mmr-measles-mumps-rubella-vaccine-advice-for-pregnant-women

3) Многие другие уважаемые источники - едины во мнении "специально беременных прививать нельзя, но если случайно привили - это не повод для аборта, ничего плохого, скорее всего, не случится":
https://www.cdc.gov/mmwr/preview/mmwrhtml/00001385.htm
https://www.cdc.gov/mmwr/preview/mmwrhtml/00001154.htm
https://academic.oup.com/jid/article/204/suppl_2/S713/874342
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1119900/
https://www.who.int/vaccine_safety/publications/safety_pregnancy_nov2014.pdf
https://www.ncbi.nlm.nih.gov/pubmed/?term=1669784
https://onlinelibrary.wiley.com/doi/abs/10.1002/ajmg.a.30225
и тд

Так что если такая ситуация случилась с вашей пациенткой - можете ее успокоить, скорее всего ничего плохого не случится, и уж тем более не нужно прерывать беременность только по этой причине.