Atherosclerosis - the main source of vascular problems Most pathologies of the peripheral arteries are in one way or another associated with the formation of atherosclerotic plaques. They interfere with the normal blood supply to tissues, can provoke local inflammation, and can simply break off, becoming a deadly embolus. Still, not all arterial diseases are related to excess cholesterol👇🏻 For example, endarteritis (most commonly found in the lower extremities). A pathology that develops due to dystrophy of nerve endings, leading to excessive narrowing of the vascular lumen. At the initial stage of endarteritis tissues from oxygen starvation are saved by collaterals - small vessels that bypass the "main highway". However, later they also begin to spasm (narrowing). Then a person begins to feel coldness in the legs, increased fatigue, limping, and soon pain, which will gradually intensify.