What aches in the head when it hurts? After all, there are no pain receptors in it🤔 That's right, but they are present in various tissues of the head. Especially the walls of blood vessels and the dura mater are rich in them. The latter is the connective tissue "cover" that covers the brain. This means that the pain is mainly due to increased arterial and intracranial pressure. This leads to overstretching of tissues and activation of pain receptors in them.