Intelligence has no effect on brain size So, you can forget all "interesting facts about famous people"🙌🏻 Intelligence is the sum of qualities: the ability to comprehend, understand, think through, remember, then recall, infer, extrapolate, or relate to something else entirely... It could be said that intelligence depends to a large extent on the activity of associative connections in the brain. But it is worth saying that intelligence depends on heredity - with 52 genes that form it.