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Eye πŸ‘ Surgery (ophthalmology)

232 @eye_surg

Eye Surgery ΠΏΡ€ΠΎΡ„Π΅ΡΡΠΈΠΎΠ½Π°Π»ΡŒΠ½ΠΎΠ΅ сообщСство Π²Ρ€Π°Ρ‡Π΅ΠΉ-ΠΎΡ„Ρ‚Π°Π»ΡŒΠΌΠΎΠ»ΠΎΠ³ΠΎΠ², ΠΎΡ„Ρ‚Π°Π»ΡŒΠΌΠΎΡ…ΠΈΡ€ΡƒΡ€Π³ΠΎΠ².

Eye πŸ‘ Surgery (ophthalmology)

4 Π³ΠΎΠ΄Π° Π½Π°Π·Π°Π΄
ΠžΡ‚ΠΊΡ€Ρ‹Ρ‚ΡŒ Π²
ВоксичСн Π»ΠΈ Ρ‚Ρ€ΠΈΠΏΠ°Π½ΠΎΠ²Ρ‹ΠΉ синий для ΠΊΠ»Π΅Ρ‚ΠΎΠΊ ΠΏΠ΅Ρ€Π΅Π΄Π½Π΅Π³ΠΎ ΠΎΡ‚Ρ€Π΅Π·ΠΊΠ° Π³Π»Π°Π·Π°? Π’Ρ‹Π·Ρ‹Π²Π°Π΅Ρ‚ Π»ΠΈ ΠΎΠ½ Π½Π΅ΠΆΠ΅Π»Π°Ρ‚Π΅Π»ΡŒΠ½Ρ‹Π΅ послСдствия для Π³Π»Π°Π·? Π”Π°, Ρ‚Ρ€ΠΈΠΏΠ°Π½ΠΎΠ²Ρ‹ΠΉ синий Π² Ρ†Π΅Π»ΠΎΠΌ токсичный. ΠŸΡ€ΠΈ Π΄Π»ΠΈΡ‚Π΅Π»ΡŒΠ½ΠΎΠΌ воздСйствии ΠΈ/ΠΈΠ»ΠΈ высоких концСнтрациях ΠΎΠ½ ΠΌΠΎΠΆΠ΅Ρ‚ Π²Ρ‹Π·Ρ‹Π²Π°Ρ‚ΡŒ Π΄Π°ΠΆΠ΅ гибСль ΠΊΠ»Π΅Ρ‚ΠΎΠΊ. Однако, ΠΏΡ€ΠΈ использовании краситСля Π² Ρ‚Π΅Ρ‡Π΅Π½ΠΈΠ΅ 10 сСкунд Π² ΠΊΠΎΠ½Ρ†Π΅Π½Ρ‚Ρ€Π°Ρ†ΠΈΠΈ 0,1% ΠΈΠ»ΠΈ ΠΌΠ΅Π½Π΅Π΅ ΠΈΠΌΠ΅Π΅Ρ‚ высокий ΠΏΡ€ΠΎΡ„ΠΈΠ»ΡŒ бСзопасности. Π—Π° 20 Π»Π΅Ρ‚ использования краситСля ΠΏΡ€ΠΈ ΠΎΠΊΡ€Π°ΡˆΠΈΠ²Π°Π½ΠΈΠΈ капсулы хрусталика, Π° это дСсятки ΠΌΠΈΠ»Π»ΠΈΠΎΠ½ΠΎΠ² случаСв (Π° ΠΌΠΎΠΆΠ΅Ρ‚ ΠΈ сотни), сущСствуСт Π΅Π΄ΠΈΠ½ΠΈΡ‡Π½Ρ‹Π΅ сообщСния ΠΎ ΠΏΠΎΠ±ΠΎΡ‡Π½Ρ‹Ρ… дСйствиях. Π’ основном, ΠΏΠΎΠ±ΠΎΡ‡Π½Ρ‹Π΅ дСйствия Π±Ρ‹Π»ΠΈ Ρ€Π΅Π·ΡƒΠ»ΡŒΡ‚Π°Ρ‚ΠΎΠΌ использования Π½Π΅ сСртифицированных расходных ΠΌΠ°Ρ‚Π΅Ρ€ΠΈΠ°Π»ΠΎΠ² ΠΈΠ»ΠΈ попадания краситСля Π² Π²ΠΈΡ‚Ρ€Π΅Π°Π»ΡŒΠ½ΡƒΡŽ ΠΏΠΎΠ»ΠΎΡΡ‚ΡŒ. πŸ“ Google Translate. Is trypan blue toxic to cells in the anterior segment of the eye? Does it cause undesirable effects on the eyes? Yes, trypan blue is generally toxic. With prolonged exposure and/or high concentrations, it can even cause cell death. However, when using the dye for 10 seconds at a concentration of 0.1% or less, it has a high safety profile. For 20 years of using the dye to stain the lens capsule, and these are tens of millions of cases (maybe hundreds), there are isolated reports of side effects. In general, side effects were the result of the use of non-certified consumables or the ingress of dye into the vitreous cavity. Бсылки: 1. Effects of trypan blue on cell viability and gene expression in human retinal pigment epithelial cells. 2. Effect of intraoperative trypan blue on lens epithelial cells – Histomorphological analysis. 3. Trypan blue-associated retinal toxicity post complicated cataract surgery 4. Determining the lowest trypan blue concentration that satisfactorily stains the anterior capsule. 5. Safety of trypan blue 1% and indocyanine green 0.5% in assisting visualization of anterior capsule during phacoemulsification in mature cataract. 6. Effect of intraoperative trypan blue on lens epithelial cells – Histomorphological analysis. 7. Non-infectious endophthalmitis associated with trypan blue use in cataract surgery. 8. Two cases of toxic anterior segment syndrome from generic trypan blue. 9. Trypan blue dye for anterior segment surgeries. 10. Biocompatibility of trypan blue with human corneal cells.
Effects of trypan blue on cell viability and gene expression in human retinal pigment epithelial cells

Aim: To evaluate the effects of trypan blue on cell viability and gene expression in human retinal pigment epithelial (RPE) cells.Methods: Three concentrations (0.06 mg/ml, 0.6 mg/ml, and 4 mg/ml) of trypan blue were applied ...

PubMed Central (PMC)